Ammonia → 3-Chlorobenzene-1-carboximidamide hydrochloride
反応式
Cl.[Cl:2][C:3]1[CH:4]=[C:5]([C:9](=[NH:13])OCC)[CH:6]=[CH:7][CH:8]=1.[NH3:14]>>[ClH:2].[Cl:2][C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[C:9]([NH2:13])=[NH:14]参加物
3
実験手順
A 18-mL vial was charged with ethyl 3-chlorobenzenecarboximidate hydrochloride (450 mg, 2 mmol, 1 eq.) and NH3 (2N in ethanol, 12 ml, 24 mmol, 12 eq.). The resulting mixture was stirred at rt overnight. The volatile material was removed under reduced pressure and the product thus obtained was forwarded to the next step without any further purification.
後処理
- customThe volatile material was removed under reduced pressure
- customthe product thus obtained
- customwas forwarded to the next step without any further purification
出典と根拠
- ORDレコード
- ord-4d1cf10ee67a47b89e4b888b066b2fbe
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09221843B2
反応ノート
読み込み中…