Cyanamide → HCID 178512257、化合物

HRID 1508700ノート

反応式

HRID 1508700 の反応式
[Cl:1][C:2]1[S:6][C:5]([C:7]#[N:8])=[CH:4][CH:3]=1.O(C)[Na].[NH2:12][C:13]#N.[NH4+:15].[Cl-]>CO>[Cl:1][C:2]1[S:6][C:5]([C:7](=[NH:15])[NH:8][C:13]#[N:12])=[CH:4][CH:3]=1

参加物

6

反応物 4

HCID 9864CyanamideHCID 25517Ammonium ChlorideHCID 122032655-Chloro-2-thiophenecarbonitrileHCID 178418582HCID 178418582、化合物

生成物 1

HCID 178512257HCID 178512257、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a solution of 5-chlorothiophene-2-carbonitrile 1 in MeOH was added NaOCH3. The reaction mixture was stirred at room temperature for 4 h and then NH2CN was added. The reaction was allowed stir for overnight under N2. The mixture was then poured into NH4Cl (aq) and the precipitate collected and washed with water. The dried sample was confirmed as desired product 5-chloro-N-cyanothiophene-2-carboximidamide 2.

後処理

  1. stirringThe reaction was allowed stir for overnight under N2
  2. customthe precipitate collected
  3. washwashed with water

出典と根拠

ORDレコード
ord-2b2e2c1a069d4abc9fd26b833e6bcf8c
出典データセット
uspto-grants-2015_12
特許番号
US09221843B2

反応ノート

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