N-methyl-2-pyrrolidone → N'-(2-Amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)furan-2-carbohydrazide

反応式

[CH3:37][N:38]1[CH2:39][CH2:40][CH2:41][C:42]1=[O:43].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([NH2:8])[n:7]1)[n:9]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][N:17]([c:20]3[c:21]([F:27])[cH:22][c:23]([F:26])[cH:24][cH:25]3)[CH2:18][CH2:19]1)[cH:10][cH:11]2.[o:28]1[c:29]([C:33](=[O:34])[NH:35][NH2:36])[cH:30][cH:31][cH:32]1>>[c:2]1([NH:36][NH:35][C:33]([c:29]2[o:28][cH:32][cH:31][cH:30]2)=[O:34])[c:3]2[c:4]([n:5][c:6]([NH2:8])[n:7]1)[n:9]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][N:17]([c:20]3[c:21]([F:27])[cH:22][c:23]([F:26])[cH:24][cH:25]3)[CH2:18][CH2:19]1)[cH:10][cH:11]2