Hydrazine → 3-Hydrazinyl-4-methyl-6-phenylpyridazine
反応式
Cl[C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][C:7]=1[CH3:8].[NH2:15][NH2:16]>>[CH3:8][C:7]1[CH:6]=[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:4]=[N:3][C:2]=1[NH:15][NH2:16]参加物
3
反応条件
- 温度
- 100 °C
実験手順
3-Chloro-4-methyl-6-phenylpyridazine (0.510 g, 2.49 mmol) was dissolved in hydrazine (1.56 ml, 49.8 mmol) then the reaction mixture was heated at 100° C. for 1.5 hours. The precipitate that had formed in the mixture was collected and washed with iPrOH. The solid was dried under high vacuum to afford 1-(4-methyl-6-phenylpyridazin-3-yl)hydrazine as a pale yellow solid.
後処理
- customThe precipitate that had formed in the mixture
- customwas collected
- washwashed with iPrOH
- customThe solid was dried under high vacuum
出典と根拠
- ORDレコード
- ord-626bd2b5981847049f721ee0b4974d61
- 出典データセット
- uspto-grants-2012_07
- 特許番号
- US08212041B2
反応ノート
読み込み中…