2-Methylhept-6-en-2-amine → N-{[(1,1-Dimethylhex-5-enyl)amino]carbonyl}-3-methyl-L-valine

反応式

[CH3:1][C:2]([CH3:18])([CH3:17])[C@@H:3]([C:14]([OH:16])=[O:15])[NH:4][C:5](N(C)CCCC=C)=[O:6].[CH3:19][C:20]([NH2:27])([CH2:22][CH2:23][CH2:24][CH:25]=[CH2:26])[CH3:21]>>[CH3:19][C:20]([NH:27][C:5]([NH:4][C@H:3]([C:14]([OH:16])=[O:15])[C:2]([CH3:1])([CH3:17])[CH3:18])=[O:6])([CH3:21])[CH2:22][CH2:23][CH2:24][CH:25]=[CH2:26]

参加物

反応物 2

HCID 156804042-Methylhept-6-en-2-amine

HCID 574311913-Methyl-N-[methyl(pent-4-en-1-yl)carbamoyl]-L-valine

生成物 1

HCID 57692647N-{[(1,1-Dimethylhex-5-enyl)amino]carbonyl}-3-methyl-L-valine

実験手順

N-{[(1,1-Dimethylhex-5-enyl)amino]carbonyl}-3-methyl-L-valine was prepared according to the procedure for 3-methyl-N-{[methyl(pent-4-enyl)amino]carbonyl}-L-valine (Steps 4-5) by using 2-methylhept-6-en-2-amine instead of N-methylpent-4-en-1-amine in Step 4.

出典と根拠

ORDレコード: ord-76a2e7804cb345758ad43fc82d41e813
出典データセット: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08216999B2

反応ノート

読み込み中…