2,2-Dimethylhex-5-en-1-ol → (2S)-({[(2,2-Dimethylhex-5-en-1-yl)oxy]carbonyl}amino)(1-methylcyclohexyl)acetic acid

HRID 1511581

反応式

HRID 1511581 の反応式
CC(C)(C)[C@@H](C(O)=O)N[C:5](OCCCC=C)=[O:6].Cl.[NH2:19][C@@H:20]([C:24]1([CH3:30])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1)[C:21]([OH:23])=[O:22].[CH3:31][C:32]([CH3:39])([CH2:35][CH2:36][CH:37]=[CH2:38])[CH2:33][OH:34]>>[CH3:31][C:32]([CH3:39])([CH2:35][CH2:36][CH:37]=[CH2:38])[CH2:33][O:34][C:5]([NH:19][C@@H:20]([C:24]1([CH3:30])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1)[C:21]([OH:23])=[O:22])=[O:6]

参加物

4

反応物 3

HCID 102408212,2-Dimethylhex-5-en-1-olHCID 453799283-Methyl-N-{[(pent-4-en-1-yl)oxy]carbonyl}-L-valineHCID 57462912(S)-2-Amino-2-(1-methylcyclohexyl)acetic acid hydrochloride

生成物 1

HCID 45379613(2S)-({[(2,2-Dimethylhex-5-en-1-yl)oxy]carbonyl}amino)(1-methylcyclohexyl)acetic acid

実験手順

(2S)-({[(2,2-Dimethylhex-5-en-1-yl)oxy]carbonyl}amino)(1-methylcyclohexyl)acetic acid was prepared according to the procedure for 3-methyl-N-[(pent-4-enyloxy)carbonyl]-L-valine using (2S)-amino(1-methylcyclohexyl)acetic acid-HCl and 2,2-dimethylhex-5-en-1-ol. LRMS (ESI) m/z 326.3 [(M+H)+; calcd for C18H32NO4: 326.2].

出典と根拠

ORDレコード
ord-5683f704c6584a37a2ce6346ec4ca42e
出典データセット
uspto-grants-2012_07
特許番号
US08216999B2

関連ノート

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