Ethyl formate → HCID 86639223、化合物
反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11].[CH:15](OCC)=[O:16]>C1(C)C=CC=CC=1>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][N:7]([CH:15]=[O:16])[CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11]参加物
4
実験手順
Ethyl 3-[(thiophen-2-ylmethyl)amino]propionate (13.8 g) prepared in the step 1 and 47.8 g of ethyl formate were dissolved in 100 mL of toluene and heated to reflux overnight. After the reaction solution was cooled, the solvent was evaporated therefrom in vacuo to give 15.6 g of the objective compound as light yellow liquid.
後処理
- temperatureheated
- temperatureto reflux overnight
- temperatureAfter the reaction solution was cooled
- customthe solvent was evaporated
出典と根拠
- ORDレコード
- ord-bc2babd608984d479558c4097b7a0a7d
- 出典データセット
- uspto-grants-2012_07
- 特許番号
- US08217031B2
反応ノート
読み込み中…