1,2-Dichloro-4-fluorobenzene → 7-(3,4-Dichlorophenyloxy)-5-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
反応式
[CH3:1][N:2]1[CH2:7][CH:6]([OH:8])[C:5]2[S:9][CH:10]=[CH:11][C:4]=2[CH2:3]1.[Cl:12][C:13]1[CH:14]=[C:15](F)[CH:16]=[CH:17][C:18]=1[Cl:19]>>[Cl:12][C:13]1[CH:14]=[C:15]([O:8][CH:6]2[CH2:7][N:2]([CH3:1])[CH2:3][C:4]3[CH:11]=[CH:10][S:9][C:5]2=3)[CH:16]=[CH:17][C:18]=1[Cl:19]参加物
3
実験手順
The same method as in Example 1 was conducted using 5-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 14) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
後処理
- customto give the objective compound
出典と根拠
- ORDレコード
- ord-29225fbe417b41c5ae68c12e4d6c483c
- 出典データセット
- uspto-grants-2012_07
- 特許番号
- US08217031B2
反応ノート
読み込み中…