1,2-Dichloro-4-fluorobenzene → 4-(3,4-Dichlorophenyloxy)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

HRID 1511635

反応式

HRID 1511635 の反応式
[S:1]1[C:5]2[CH2:6][NH:7][CH2:8][CH:9]([OH:10])[C:4]=2[CH:3]=[CH:2]1.[Cl:11][C:12]1[CH:13]=[C:14](F)[CH:15]=[CH:16][C:17]=1[Cl:18]>>[Cl:11][C:12]1[CH:13]=[C:14]([O:10][CH:9]2[CH2:8][NH:7][CH2:6][C:5]3[S:1][CH:2]=[CH:3][C:4]2=3)[CH:15]=[CH:16][C:17]=1[Cl:18]

参加物

3

反応物 2

HCID 740281,2-Dichloro-4-fluorobenzeneHCID 123370234,5,6,7-Tetrahydrothieno[2,3-c]pyridin-4-ol

生成物 1

HCID 684132074-(3,4-Dichlorophenyloxy)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

実験手順

The same method as in Example 1 was conducted using 4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 5) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.

後処理

  1. customto give the objective compound

出典と根拠

ORDレコード
ord-d06b5ce26b134463806893cb1732c61b
出典データセット
uspto-grants-2012_07
特許番号
US08217031B2

関連ノート

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