Benzene, 1,2-dichloro-3-fluoro- → 4-(2,3-Dichlorophenyloxy)-2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine

HRID 1511686

反応式

HRID 1511686 の反応式
[CH3:1][C:2]1[O:13][C:5]2[CH2:6][N:7]([CH3:12])[CH2:8][CH2:9][CH:10]([OH:11])[C:4]=2[CH:3]=1.[Cl:14][C:15]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:16]=1F>>[Cl:14][C:15]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:16]=1[O:11][CH:10]1[CH2:9][CH2:8][N:7]([CH3:12])[CH2:6][C:5]2[O:13][C:2]([CH3:1])=[CH:3][C:4]1=2

参加物

3

反応物 2

HCID 119011Benzene, 1,2-dichloro-3-fluoro-HCID 684101192,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol

生成物 1

HCID 250277984-(2,3-Dichlorophenyloxy)-2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine

実験手順

The same method as in Example 1 was conducted using 2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 20) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2,3-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.

後処理

  1. customto give the objective compound

出典と根拠

ORDレコード
ord-3890b5173e2847ddb4cd154cb6cc21fb
出典データセット
uspto-grants-2012_07
特許番号
US08217031B2

関連ノート

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