2-Chloro-5-fluorobenzamide → HCID 68702691、化合物
反応式
[CH3:1][C:2]1[O:12][C:5]2[CH2:6][N:7]([CH3:11])[CH2:8][CH:9]([OH:10])[C:4]=2[CH:3]=1.[C:13]([C:16]1[CH:17]=[C:18](F)[CH:19]=[CH:20][C:21]=1[Cl:22])(=[O:15])[NH2:14]>>[ClH:22].[C:13]([C:16]1[CH:17]=[C:18]([O:10][CH:9]2[CH2:8][N:7]([CH3:11])[CH2:6][C:5]3[O:12][C:2]([CH3:1])=[CH:3][C:4]2=3)[CH:19]=[CH:20][C:21]=1[Cl:22])(=[O:15])[NH2:14]参加物
3
実験手順
The same method as in Example 3 was conducted using 2,6-dimethyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 2) instead of 6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 1) and was conducted using 3-carbamoyl-4-chloro-1-fluorobenzene instead of 1,3-difluorobenzene to give the objective compound.
後処理
- customto give the objective compound
出典と根拠
- ORDレコード
- ord-257760c728bd45468bbcb37ec72ae5f1
- 出典データセット
- uspto-grants-2012_07
- 特許番号
- US08217031B2
反応ノート
読み込み中…