1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester → 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole

HRID 1513788ノート

反応式

HRID 1513788 の反応式
C(N1C=C([B:8]2[O:12][C:11]([CH3:14])([CH3:13])[C:10]([CH3:16])([CH3:15])[O:9]2)C=N1)C.Br[C:18]1[CH:19]=[N:20][N:21]([CH2:23][C:24]([F:27])([F:26])[F:25])[CH:22]=1>>[CH3:15][C:10]1([CH3:16])[C:11]([CH3:14])([CH3:13])[O:12][B:8]([C:18]2[CH:19]=[N:20][N:21]([CH2:23][C:24]([F:27])([F:26])[F:25])[CH:22]=2)[O:9]1

参加物

3

反応物 2

HCID 113790451-Ethyl-1H-pyrazole-4-boronic acid, pinacol esterHCID 610302834-bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole

生成物 1

HCID 689235864-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole

実験手順

The title compound was prepared in the same manner as 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole starting with 4-bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole.

出典と根拠

ORDレコード
ord-569c05b72f584fce9efbcd5fda5f328b
出典データセット
uspto-grants-2012_07
特許番号
US08217177B2

反応ノート

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