Benzo(B)Thiophene → 2-(5-Bromo-2-chlorobenzyl)-1-benzothiophene

反応式

[CH:1]1[CH:2]=[CH:3][C:4]2[S:9][CH:8]=[CH:7][C:5]=2[CH:6]=1.[Br:10][C:11]1[CH:12]=[CH:13][C:14]([Cl:19])=[C:15]([CH:18]=1)[CH:16]=O>>[S:9]1[C:8]([CH2:16][C:15]2[CH:18]=[C:11]([Br:10])[CH:12]=[CH:13][C:14]=2[Cl:19])=[CH:7][C:5]2[CH:6]=[CH:1][CH:2]=[CH:3][C:4]1=2

参加物

反応物 2

HCID 7221Benzo(B)Thiophene

HCID 106089255-Bromo-2-chlorobenzaldehyde

生成物 1

HCID 581784582-(5-Bromo-2-chlorobenzyl)-1-benzothiophene

実験手順

Thianaphthene and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 7 to give the target compound.

後処理

additionwere treated in a manner similar to Reference Example 7
customto give the target compound

出典と根拠

ORDレコード: ord-d91953e8271743169205a7ac16ac7138
出典データセット: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08222219B2

反応ノート

読み込み中…