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2-Bromobenzenethiol → 4-Hydroxy-4-(2-mercapto-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromobenzenethiol | HCID 80598 | — |
| 反応物 | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| 反応物 | 4-(5-Fluoro-2-mercapto-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester | HCID 68682113 | — |
| 生成物 | 4-Hydroxy-4-(2-mercapto-phenyl)-piperidine-1-carboxylic acid tert-butyl ester | HCID 68682215 | — |
反応手順
This intermediate was prepared from 2-bromo-benzenethiol and 4-oxo-piperidine-1-carboxylic acid tert-butyl ester in a similar way as described for 4-(5-fluoro-2-mercapto-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732463B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-b73883d285c14f8994f382c64271343a |
| 出典メモ | uspto-grants-2010_06 |