反応式
[CH2:1]([NH2:3])[CH3:2].[Br:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][C:6]=1[S:15](Cl)(=[O:17])=[O:16]>>[Br:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:13])([F:12])[F:14])=[CH:7][C:6]=1[S:15]([NH:3][CH2:1][CH3:2])(=[O:17])=[O:16]参加物
3
実験手順
The title compound was prepared in a manner similar to that described for Intermediate EU using ethylamine and 2-bromo-5-(trifluoromethyl)benzene-1-sulfonyl chloride. 1H NMR (500 MHz, CDCl3) δ 8.43-8.38 (m, 1H), 7.93-7.86 (dd, J=8.3, 0.9, 1H), 7.70-7.62 (m, 1H), 5.08 (s, 1H), 3.11-2.96 (m, 2H), 1.19-1.09 (t, J=7.2, 3H).
出典と根拠
- ORDレコード
- ord-b393a4b1b37e4f27af2208c4624f4c75
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09079866B2
関連ノート
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