3-Bromo-2,2-dimethylpropyl acetate → Methyl 3-(3-acetoxy-2,2-dimethylpropoxy)-5-tert-butylbenzoate

反応式

[C:1]([C:5]1[CH:6]=[C:7]([CH:12]=[C:13]([OH:15])[CH:14]=1)[C:8]([O:10][CH3:11])=[O:9])([CH3:4])([CH3:3])[CH3:2].[C:16]([O:19][CH2:20][C:21]([CH3:25])([CH3:24])[CH2:22]Br)(=[O:18])[CH3:17]>>[C:16]([O:19][CH2:20][C:21]([CH3:25])([CH3:24])[CH2:22][O:15][C:13]1[CH:12]=[C:7]([CH:6]=[C:5]([C:1]([CH3:4])([CH3:2])[CH3:3])[CH:14]=1)[C:8]([O:10][CH3:11])=[O:9])(=[O:18])[CH3:17]

参加物

反応物 2

HCID 133577153-Bromo-2,2-dimethylpropyl acetate

HCID 53399216Methyl 3-tert-butyl-5-hydroxybenzoate

生成物 1

HCID 58046018Methyl 3-(3-acetoxy-2,2-dimethylpropoxy)-5-tert-butylbenzoate

実験手順

Methyl 3-tert-butyl-5-hydroxybenzoate (O6.043; 1.79 g) was reacted with 3-bromo-2,2-dimethylpropyl acetate, worked up and purified analogously to O2.85. 1.01 g of the title compound were obtained.

後処理

custompurified analogously to O2

出典と根拠

ORDレコード: ord-c6fc161a9dba49198959435ab047a00b
出典データセット: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09079906B2

反応ノート

読み込み中…