3-(3-Chlorophenyl)-3-oxopropanenitrile → 4-chloro-3-(3-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

HRID 1525384

反応式

HRID 1525384 の反応式
[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[N:14]([CH3:24])[N:15]=[C:16](C3C=CC=CC=3Cl)[C:3]=12.[Cl:25][C:26]1[CH:27]=[C:28]([CH:34]=[CH:35][CH:36]=1)C(CC#N)=O>>[Cl:1][C:2]1[C:7]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)=[N:6][N:5]=[C:4]2[N:14]([CH3:24])[N:15]=[C:16]([C:35]3[CH:34]=[CH:28][CH:27]=[C:26]([Cl:25])[CH:36]=3)[C:3]=12

参加物

3

反応物 2

HCID 1408553-(3-Chlorophenyl)-3-oxopropanenitrileHCID 665764824-chloro-3-(2-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

生成物 1

HCID 665765584-chloro-3-(3-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

実験手順

Compound 13 was synthesised following similar procedures outlined in Example 1 (Compound 37), using 3-chlorobenzoylacetonitrile instead of 2-chlorobenzoyl acetonitrile in Step 1.

出典と根拠

ORDレコード
ord-522bb3bacccf40b583190480439345f6
出典データセット
uspto-grants-2015_07
特許番号
US09079909B2

関連ノート

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