Benzyl methyl(15-phenylpentadec-5-en-1-yl)carbamate → N-methyl-15-phenylpentadecane-1-amine

HRID 1525801ノート

反応式

HRID 1525801 の反応式
[CH3:1][N:2]([CH2:13][CH2:14][CH2:15][CH2:16][CH:17]=[CH:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)C(=O)OCC1C=CC=CC=1>C(O)C.[C].[Pd]>[CH3:1][NH:2][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

参加物

4

反応物 1

HCID 86722744Benzyl methyl(15-phenylpentadec-5-en-1-yl)carbamate

生成物 1

HCID 86722746N-methyl-15-phenylpentadecane-1-amine収率 65.4%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

Compound 15 (2.6 g) was dissolved in ethanol (20 mL) and 5% palladium carbon (260 mg) was added thereto, followed by stirring at room temperature for 3.5 hours under hydrogen atmosphere. The reaction solution was replaced with argon atmosphere, filtered with Celite (brand name) and concentrated under reduced pressure to obtain the title compound (1.2 g) having the following physical property values.

後処理

  1. filtrationfiltered with Celite (brand name)
  2. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-7150da1bcaca4e0598449b3849a594d1
出典データセット
uspto-grants-2015_07
特許番号
US09085523B2

反応ノート

読み込み中…