Salicylaldehyde → 3-(4-Methoxybenzoyl)-2H-1-benzopyran-2-one
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:16])[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:5][CH:4]=1.N1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1.OC1C=CC=CC=1C=O>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]([C:10]2[C:11](=[O:12])[O:13][C:14]3[C:21]([CH:22]=2)=[CH:20][CH:19]=[CH:18][CH:15]=3)=[O:16])=[CH:7][CH:8]=1参加物
5
実験手順
3.64 g (16.38 mmol) of ethyl 3-(4-methoxyphenyl)-3-oxopropanoate and 1.39 g of piperidine (16.38 mmol) are added to a solution of 2 g (16.38 mmol) of 2-hydroxybenzaldehyde in 15 ml of ethanol. The reaction mixture is stirred for 8 hours at reflux. The solution is cooled, and then the white solid formed is filtered and rinsed with a minimum of ethanol to yield 4.02 g (88%) of 3-(4-methoxybenzoyl)-2H-chromen-2-one.