[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]([C:9]2[C:10](=[O:19])[O:11][C:12]3[C:17]([CH:18]=2)=[CH:16][CH:15]=[CH:14][CH:13]=3)=O)=[CH:5][CH:4]=1.[NH2:22][C:23]1[CH:27]=[C:26]([CH3:28])[NH:25][N:24]=1.C([O-])(=O)C.[NH4+].C(OCC)C>C(O)(=O)C.CO>[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]2[N:22]=[C:23]3[NH:24][N:25]=[C:26]([CH3:28])[C:27]3=[C:18]3[C:17]4[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=4[O:11][C:10](=[O:19])[C:9]=23)=[CH:5][CH:4]=1A mixture of 2.1 g (7.49 mmol) of 3-(4-methoxybenzoyl)-2H-chromen-2-one with 728 mg (7.49 mmol) of 3-amino-5-methyl-pyrazole in 15 ml of acetic acid is heated at 110° C. for 10 minutes. 2.3 g (30 mmol) of ammonium acetate is then added and then the mixture is carried at 150° C. for 3 h. The solution is placed at room temperature and then 30 ml of ethyl ether and 5 ml of methanol are added. The white solid formed is filtered and then rinsed with diethyl ether to yield 810 mg of 5-(4-methoxyphenyl)-1-methylchromeno[4,3-d]pyrazolo[3,4-b]pyridin-6(3H)-one.
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