Hydrochloric Acid → (3-Aminomethyl-5-chloro-4-fluoro-benzyl)-(2-methoxy-ethyl)-methyl-amine
反応式
C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[C:13]([CH2:15][N:16]([CH2:18][CH2:19][O:20][CH3:21])[CH3:17])[CH:12]=[C:11]([Cl:22])[C:10]=1[F:23])(C)(C)C.Cl>O1CCOCC1>[NH2:7][CH2:8][C:9]1[CH:14]=[C:13]([CH:12]=[C:11]([Cl:22])[C:10]=1[F:23])[CH2:15][N:16]([CH2:18][CH2:19][O:20][CH3:21])[CH3:17]参加物
4
実験手順
was prepared according to Scheme C2 (step D) from (3-chloro-2-fluoro-5-{[(2-methoxy-ethyl)-methyl-amino]-methyl}-benzyl)-carbamic acid tert-butyl ester (222 mg, 0.47 mmol) and 4N HCl in dioxane. MS (LC-MS): 261.0 [M]+.
後処理
- customwas prepared
出典と根拠
- ORDレコード
- ord-5028cc5dffa44f6b817a21bffc4b85d7
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09085555B2
反応ノート
読み込み中…