Hydrochloric Acid → N-(3-Aminomethyl-5-chloro-4-fluoro-benzyl)-N,N',N'-trimethyl-ethane-1,2-diamine
反応式
C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[C:13]([CH2:15][N:16]([CH2:18][CH2:19][N:20]([CH3:22])[CH3:21])[CH3:17])[CH:12]=[C:11]([Cl:23])[C:10]=1[F:24])(C)(C)C.Cl>O1CCOCC1>[NH2:7][CH2:8][C:9]1[CH:14]=[C:13]([CH:12]=[C:11]([Cl:23])[C:10]=1[F:24])[CH2:15][N:16]([CH3:17])[CH2:18][CH2:19][N:20]([CH3:22])[CH3:21]参加物
4
実験手順
was prepared according to Scheme C2 (step D) from (3-chloro-5-{[(2-dimethylamino-ethyl)-methyl-amino]-methyl}-2-fluoro-benzyl)-carbamic acid tert-butyl ester (228 mg, 0.51 mmol) and 4N HCl in dioxane. MS (LC-MS): 274.0 [M]+.
後処理
- customwas prepared
出典と根拠
- ORDレコード
- ord-c8b2878bc0314b40bd2a01b2d3d50eee
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09085555B2
反応ノート
読み込み中…