Dimethylamine → HCID 67997831、化合物
反応式
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([C:11]([OH:13])=O)[CH2:10][CH2:9]2)=[N:6][CH:7]=1.[CH3:14][NH:15][CH3:16]>>[CH3:14][N:15]([CH3:16])[C:11]([C:8]1([C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][N:6]=2)[CH2:10][CH2:9]1)=[O:13]参加物
3
実験手順
The title compound was prepared from 1-(5-bromo-pyridin-2-yl)-cyclopropanecarboxylic acid and dimethylamine (2 mol/L in tetrahydrofuran) following a procedure analogous to that described in Step 2 for Intermediate 5. Yield: quantitative; LC (method 1): tR=1.65 min; Mass spectrum (ESI+): m/z=269/271 (Br) [M+H]+.
出典と根拠
- ORDレコード
- ord-96dd983e097d433eacfd7bff421ddf0e
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09090605B2
反応ノート
読み込み中…