4-(3,3,3-Trifluoropropyl)phenol → HCID 21252690、化合物
反応式
[H][H].[F:3][C:4]([F:15])([F:14])[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1>C(O)(C)C.[Rh]>[F:3][C:4]([F:14])([F:15])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9][CH2:8]1参加物
5
実験手順
At 50° C. and 150 bar hydrogen pressure, 40.7 g of 4-(3,3,3-trifluoropropyl)phenol in 800 ml of isopropanol were hydrogenated using rhodium on carbon as catalyst for 20 h. The catalyst was filtered off and the reaction solution was concentrated, to give the title product as a colourless solid which was reacted further without any purification.
後処理
- customAt 50° C.
- customfor 20 h
- filtrationThe catalyst was filtered off
- concentrationthe reaction solution was concentrated
出典と根拠
- ORDレコード
- ord-7060604328b04fffb52ac74b1780025b
- 出典データセット
- uspto-grants-2001_03
- 特許番号
- US06197729B1
反応ノート
読み込み中…