Hepta-1,6-dien-4-amine → N-(N,N-Dimethyl-N-dodecylammonio)butyldiallylmethylammonium Chloride Bromide

HRID 1532523

反応式

HRID 1532523 の反応式
[CH2:1]([CH:4]([NH2:8])[CH2:5][CH:6]=[CH2:7])[CH:2]=[CH2:3].[Br-:9].[Cl:10][CH2:11][CH2:12][CH2:13][CH2:14][N+:15]([CH3:29])([CH3:28])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>CO>[Br-:9].[Cl-:10].[CH3:28][N+:15]([CH2:14][CH2:13][CH2:12][CH2:11][NH2+:8][CH:4]([CH2:5][CH:6]=[CH2:7])[CH2:1][CH:2]=[CH2:3])([CH3:29])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]

参加物

4

反応物 2

HCID 12791689Hepta-1,6-dien-4-amine2 回HCID 158701334-Chlorobutyldimethyldodecylammonium bromide

生成物 1

HCID 86593803N-(N,N-Dimethyl-N-dodecylammonio)butyldiallylmethylammonium Chloride Bromide収率 67.2%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

反応条件

温度
65 °C

実験手順

A mixture of 22 g diallylmethylamine and 75 g 4-chlorobutyldimethyldodecylammonium bromide were dissolved in 100 mL methanol and the reaction mixture was stirred at 65° C. for 48 hours. The progress of the reaction was monitored by the disappearance of the diallylmethylamine by thin layer chromatography (TLC). After cooling to room temperature, the solvent was removed under reduced pressure. The residual viscous oil was precipitated into 800 mL dry ether with rapid stirring. The ether layer was decanted and the residue was again treated with 500 mL dry ether. After stirring for 15 minutes the solvent was removed and the oily residue was dried under vacuum at 35° C. for 48 hours, yielding 65 g of the product.

後処理

  1. temperatureAfter cooling to room temperature
  2. customthe solvent was removed under reduced pressure
  3. customThe residual viscous oil was precipitated into 800 mL dry ether with rapid stirring
  4. customThe ether layer was decanted
  5. additionthe residue was again treated with 500 mL dry ether
  6. stirringAfter stirring for 15 minutes the solvent
  7. customwas removed
  8. customthe oily residue was dried under vacuum at 35° C. for 48 hours

出典と根拠

ORDレコード
ord-9391c00cc64847a195d8f270f002dc2a
出典データセット
uspto-grants-2001_03
特許番号
US06203785B1

関連ノート

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