HCID 15518370、化合物 → HCID 22013785、化合物

HRID 1532646ノート

反応式

HRID 1532646 の反応式
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:39])[CH3:38])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

参加物

4

反応物 2

HCID 15518370HCID 15518370、化合物HCID 21866389Hydrogen chloride-ethyl acetate

生成物 1

HCID 22013785HCID 22013785、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

4N Hydrochloric acid/ethyl acetate solution (0.11 ml) was added to a solution containing 3-(2-henicosyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-propanamine (0.20 g) in ethyl acetate (2 ml). After being stirred for 20 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethanol-ethyl acetate, thereby yielding the entitled compound (0.19 g) as white solid.

後処理

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethanol-ethyl acetate

出典と根拠

ORDレコード
ord-91669861cc894b55a7fdec9684bdd122
出典データセット
uspto-grants-2001_03
特許番号
US06204264B1

反応ノート

読み込み中…