N,N-Dimethyl-1,3-propanediamine → HCID 9892129、化合物
反応式
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH2:6].[CH2:8]([N:26]1[C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=2[N:28]=[C:27]1[C:35](OCC)=[O:36])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>>[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH:6][C:35]([C:27]1[N:26]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=2[N:28]=1)=[O:36]参加物
3
反応条件
- 温度
- 125 °C
実験手順
N,N-Dimethyl-1,3-propanediamine (0.818 g) was added to ethyl 1-octadecyl-1H-benzimidazole-2-carboxylate (1.771 g) and the mixture was stirred for 15 hours at 125° C. The reaction mixture was purified by silica gel column chromatography (silica gel 60 g, chloroform:methanol=30:1), thereby yielding the entitled compound (1.746 g) as pale yellow oil.
後処理
- customThe reaction mixture was purified by silica gel column chromatography (silica gel 60 g, chloroform:methanol=30:1)