N,N-Dimethylethylenediamine → HCID 22013736、化合物

HRID 1532689ノート

反応式

HRID 1532689 の反応式
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH2:5].Cl[C:8]1[CH:17]=[CH:16][C:11]([C:12]([NH:14][CH3:15])=[O:13])=[CH:10][C:9]=1[N+:18]([O-:20])=[O:19]>C(OCC)(=O)C>[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH:5][C:8]1[CH:17]=[CH:16][C:11]([C:12]([NH:14][CH3:15])=[O:13])=[CH:10][C:9]=1[N+:18]([O-:20])=[O:19]

参加物

4

反応物 2

HCID 66053N,N-DimethylethylenediamineHCID 7992864-chloro-N-methyl-3-nitrobenzamide

生成物 1

HCID 22013736HCID 22013736、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

反応条件

温度
100 °C

実験手順

N,N-Dimethylethylenediamine (3.30 ml) was added to 4-chloro-N-methyl-3-nitrobenzamide (3.220 g) and the mixture was stirred for 14 hours at 100° C. The reaction mixture, with ethyl acetate added thereto, was washed with 1N sodium hydroxide aqueous solution and saturated brine successively, dried over sodium sulfate anhydride, and concentrated, thereby yielding the entitled compound (3.687 g) as yellowish orange solid.

後処理

  1. washwas washed with 1N sodium hydroxide aqueous solution and saturated brine successively
  2. dry with materialdried over sodium sulfate anhydride
  3. concentrationconcentrated

出典と根拠

ORDレコード
ord-654257d6142042fdb74bfa23f2db7568
出典データセット
uspto-grants-2001_03
特許番号
US06204264B1

反応ノート

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