HCID 22013773、化合物 → HCID 22013746、化合物

HRID 1532695ノート

反応式

HRID 1532695 の反応式
[CH3:1][N:2]([CH3:20])[CH2:3][CH2:4][NH:5][C:6]1[CH:16]=[CH:15][C:9]([C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[CH:8][C:7]=1[N+:17]([O-])=O>C(O)C.[C].[Pd]>[NH2:17][C:7]1[CH:8]=[C:9]([CH:15]=[CH:16][C:6]=1[NH:5][CH2:4][CH2:3][N:2]([CH3:20])[CH3:1])[C:10]([N:12]([CH3:14])[CH3:13])=[O:11]

参加物

4

反応物 1

HCID 22013773HCID 22013773、化合物

生成物 1

HCID 22013746HCID 22013746、化合物収率 103.3%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

10% of palladium-carbon (0.535 g) was added to a solution containing 4-{[2-(dimethylamino)ethyl]amino}-N,N-dimethyl-3-nitrobenzamide (2.672 g) in ethanol (27 ml) and the mixture was stirred for 5.5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (2.464 g) as blackish brown oil.

後処理

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-89184bdc515949dbb33433a613935788
出典データセット
uspto-grants-2001_03
特許番号
US06204264B1

反応ノート

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