Benzyl Isothiocyanate → HCID 11350308、化合物

反応式

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[CH3:13])[N:9]=[CH:8][N:7]=[C:6]2[N:14]1[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1.[CH2:20]([N:27]=[C:28]=[S:29])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:20]([NH:27][C:28]([N:17]1[CH2:16][CH2:15][N:14]([C:6]2[C:5]3[C:10](=[CH:11][C:12]([CH3:13])=[C:3]([O:2][CH3:1])[CH:4]=3)[N:9]=[CH:8][N:7]=2)[CH2:19][CH2:18]1)=[S:29])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

反応物 2

HCID 2346Benzyl Isothiocyanate

HCID 22707665HCID 22707665、化合物

生成物 1

HCID 11350308HCID 11350308、化合物収率 37%

実験手順

Substantially the same procedure as in Example 1 was repeated, except that 6-methoxy-7-methyl-4-(1-piperazinyl)quinazoline was used in place of 6,7-dimethoxy-4-(1-piperazinyl)quinazoline in Example 125, and the corresponding benzyl isothiocyanate was used in place of phenyl isocyanate, to give the desired compound.

出典と根拠

ORDレコード: ord-3840604519c24062b8f4b1885f437031
出典データセット: uspto-grants-2001_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06207667B1

反応ノート

読み込み中…