Ammonia → 2-amino N-(2-mercaptoethyl) propionamide

HRID 1533844ノート

反応式

HRID 1533844 の反応式
Cl.Cl.[NH2:3][C@H:4]([C:6](OCCN)=[S:7])C.C[C@@H:13]([OH:19])[C@H:14]([NH2:18])[C:15](O)=O.N>C(O)(C)C>[NH2:18][CH:14]([CH3:15])[C:13]([NH:3][CH2:4][CH2:6][SH:7])=[O:19]

参加物

5

反応物 3

HCID 222AmmoniaHCID 6288L-ThreonineHCID 88417728HCID 88417728、化合物

生成物 1

HCID 98555172-amino N-(2-mercaptoethyl) propionamide

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

To a suspension of 22.1 g of the 2-aminoethyl thioalaninate dihydrochloride (0.1 mole), obtained above, in 50 cm3 of isopropanol, thre are slowly added, under an inert atmosphere, 20.4 cm3 (0.15) mole) of a 2.5% aqueous ammonia solution. The resulting solution is evaporated to dryness under reduced pressure. The residue is taken up in 100 cm3 of ethanol. The insoluble ammonium chloride is separated by filtration on fritted glass. The filtrate is evaporated to dryness and dried under a vacuum at 50° C. 17.5 g of 2-amino N-(2-mercaptoethyl) propionamide in the form of a white solid whose melting point is 141° C. are obtained.

後処理

  1. customThe resulting solution is evaporated to dryness under reduced pressure
  2. customThe insoluble ammonium chloride is separated by filtration on fritted glass
  3. customThe filtrate is evaporated to dryness
  4. customdried under a vacuum at 50° C

出典と根拠

ORDレコード
ord-f1d642ddb0e54bdba47a7fb1aaa6cce4
出典データセット
uspto-grants-1992_02
特許番号
US05085860

反応ノート

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