3-Pyrrolidinecarboxamide, 2,2,5,5-tetramethyl- → 2,2,5,5-Tetramethylpyrrolidine-3-carboxylic acid

HRID 1534176ノート

反応式

HRID 1534176 の反応式
[CH3:1][C:2]1([CH3:12])[CH:6]([C:7](N)=[O:8])[CH2:5][C:4]([CH3:11])([CH3:10])[NH:3]1.[OH-:13].[Ba+2].[OH-]>>[CH3:1][C:2]1([CH3:12])[CH:6]([C:7]([OH:13])=[O:8])[CH2:5][C:4]([CH3:11])([CH3:10])[NH:3]1

参加物

3

反応物 2

HCID 697083-Pyrrolidinecarboxamide, 2,2,5,5-tetramethyl-HCID 6093286Barium hydroxide

生成物 1

HCID 126109972,2,5,5-Tetramethylpyrrolidine-3-carboxylic acid

実験手順

2,2,5,5-tetramethyl pyrroline-3-carboxylic acid was prepared by the hydrolysis of 2,2,5,5-tetramethyl pyrroline-3-carboxamide (Frinton; recrystallized from benzene) with barium hydroxide. The acid was recrystallized from water to provide an off-white solid. The measured mp was 300 (dec.) in a sealed tube; the reported mp was 300 dec. (Pauly 1902; Rozantsev 1970).

後処理

  1. customThe acid was recrystallized from water
  2. customto provide an off-white solid

出典と根拠

ORDレコード
ord-b0627d24c6a94da9be8b4645e18a4f2c
出典データセット
uspto-grants-1992_02
特許番号
US05087752

反応ノート

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