Pivalaldehyde → Retinal

HRID 1534274ノート

反応式

HRID 1534274 の反応式
[CH3:1][C:2]([CH3:6])([CH3:5])[CH:3]=O.C[C:8]([CH3:13])([CH2:11][CH3:12])[CH:9]=O.[CH2:14]([C:16]([CH3:21])([CH2:19][CH3:20])C=O)[CH3:15].[CH3:22][C:23](C)([CH2:26][CH:27]=C)C=O.CC(C)(CCC)C=[O:33].CC(C)(C=C=C)C=O>>[CH3:22][C:23]1[CH2:26][CH2:27][CH2:3][C:2]([CH3:6])([CH3:5])[C:1]=1/[CH:12]=[CH:11]/[C:8](/[CH3:13])=[CH:9]/[CH:20]=[CH:19]/[C:16](/[CH3:21])=[CH:14]/[CH:15]=[O:33]

参加物

7

反応物 6

HCID 12417Pivalaldehyde2 回HCID 776782,2-Dimethyl-3,4-pentadienalHCID 796362,2-Dimethylpent-4-enal2 回HCID 842922,2-DimethylvaleraldehydeHCID 137426Butanal, 2,2-dimethyl-HCID 15174357HCID 15174357、化合物

生成物 1

HCID 638015Retinal

実験手順

Examples of the aldehyde of the general formula (1) include trimethylacetaldehyde, 2,2-dimethylbutanal, 2-ethyl-2-methylbutanal, 2,2-dimethyl-4-pentenal, 2,2-dimethylpentanal, 2,2-dimethylpenta-3,4-dienal and the like. Particularly, trimethylacetaldehyde (boiling point 74° C. at 730 mmHg) and 2,2-dimethy-4-pentenal (boiling point 124° C. at 760 mmHg) are preferable examples of the invention because the both substances themselves and the corresponding alcohols formed at the preparation of vitamin A aldehyde as side products have lower boiling points, so that these materials can be easily removed from the reaction mixtures at lower temperatures after the completion of the reaction.

出典と根拠

ORDレコード
ord-9dce8744d086419194eb3e2a210df7f1
出典データセット
uspto-grants-1992_02
特許番号
US05087762

反応ノート

読み込み中…