Acetone → 1-[4-chloro-2-fluoro-5-(2-propynyloxy)-phenyl]-2-propoxy-4-trifluoromethyl-6(1H)-pyrimidinone

反応式

[CH2:25]([C:26]#[CH:27])[Br:28].[CH3:35][C:36](=[O:37])[CH3:38].[Cl:1][c:2]1[cH:3][c:4]([F:24])[c:5](-[n:9]2[c:10]([O:20][CH2:21][CH2:22][CH3:23])[n:11][c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[cH:6][c:7]1[OH:8].[Na+:29].[Na+:30].[O-:31][C:32](=[O:33])[O-:34]>>[Cl:1][c:2]1[cH:3][c:4]([F:24])[c:5](-[n:9]2[c:10]([O:20][CH2:21][CH2:22][CH3:23])[n:11][c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[cH:6][c:7]1[O:8][CH2:27][C:26]#[CH:25]