化工社化工社 化学情報印刷レポート · 研究参考用
Methyl Thioglycolate → Methyl 7-bromobenzo[b]thiophene-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl Thioglycolate | HCID 16907 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 3-Bromo-2-fluorobenzaldehyde | HCID 22019361 | — |
| 生成物 | Methyl 7-bromobenzo[b]thiophene-2-carboxylate | HCID 18526159 | — |
反応手順
Using 27.8 g (137.1 mmol) of 3-bromo-2-fluorobenzaldehyde, 8.2 g (205.7 mmol) of sodium hydride (60% pure) and 16.0 g (150.9 mmol) of methyl mercaptoacetate, 20.57 g of a mixture of the title compound and the corresponding acid (about 1:1) are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732477B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-c70fc1add407400192318d4fd26d8681 |
| 出典メモ | uspto-grants-2010_06 |