2-Oxazolidinone, 5,5-dimethyl- → 3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}-5,5-dimethyloxazolidin-2-one

反応式

[Br:1][c:2]1[cH:3][c:4]([F:26])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH:23]4[CH2:24][CH2:25]4)[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1.[CH3:27][C:28]1([CH3:34])[CH2:29][NH:30][C:31](=[O:33])[O:32]1>>[c:2]1([N:30]2[CH2:29][C:28]([CH3:27])([CH3:34])[O:32][C:31]2=[O:33])[cH:3][c:4]([F:26])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH:23]4[CH2:24][CH2:25]4)[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1

参加物

反応物 2

HCID 1368922-Oxazolidinone, 5,5-dimethyl-

HCID 58484842(4-Bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone

生成物 1

HCID 584846853-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}-5,5-dimethyloxazolidin-2-one

出典と根拠

ORDレコード: ord-9973738d9be445758b11cd6a47de4b83
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…