Bromobenzene → 2-(3-Bromo-phenyl)-4-methyl-6-(6-trifluoromethyl-pyridin-3-yl)-pyrimidine

反応式

[BH:19]([OH:20])[OH:21].[Br:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[Cl:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][n:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:5][c:6]([CH3:8])[n:7]1>>[c:2]1(-[c:27]2[cH:26][cH:25][cH:24][c:23]([Br:22])[cH:28]2)[n:3][c:4](-[c:9]2[cH:10][n:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:5][c:6]([CH3:8])[n:7]1

参加物

反応物 3

HCID 7961Bromobenzene

HCID 61668Boronic Acid

HCID 866246342-Chloro-4-methyl-6-(6-trifluoromethyl-pyridin-3-yl)-pyrimidine

生成物 1

HCID 673930132-(3-Bromo-phenyl)-4-methyl-6-(6-trifluoromethyl-pyridin-3-yl)-pyrimidine

出典と根拠

ORDレコード: ord-14cc56bda6cd460f8178d1fa7e823463
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…