Sodium Bicarbonate → (3,3-Diethoxy-propyl)-carbamic acid allyl ester
反応式
[C:1](Cl)(=[O:5])[CH2:2][CH:3]=C.[CH2:7]([O:9][CH:10]([O:14][CH2:15][CH3:16])[CH2:11][CH2:12][NH2:13])[CH3:8].[C:17]([O-])(O)=[O:18].[Na+]>C(Cl)Cl>[CH2:2]([O:3][C:17](=[O:18])[NH:13][CH2:12][CH2:11][CH:10]([O:14][CH2:15][CH3:16])[O:9][CH2:7][CH3:8])[CH:1]=[CH2:5]参加物
5
実験手順
But-3-enoyl chloride (930 uL, 8.84 mmol) was added slowly to a rapidly stirring mixture of 3,3-diethoxy-propylamine (1.0 g, 6.80 mmol) and NaHCO3 (2 mL of 0.6 M NaHCO3 in water) in DCM (100 mL). The reaction was stirred at room temperature overnight, then partitioned between water and DCM. The organic layer was washed several times with water and concentrated to give the crude sub-title compound that was used without further purification.
後処理
- stirringThe reaction was stirred at room temperature overnight
- custompartitioned between water and DCM
- washThe organic layer was washed several times with water
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-233d52f44e6349a7a7bc1dd57e6b77de
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07732618B2
反応ノート
読み込み中…