Dichloromethane → Methyl 2-(1,1-dimethylethyl)-2'-fluoro-5'-hydroxy-1,1'-biphenyl-4-carboxylate

反応式

[B:24]([Br:25])([Br:26])[Br:27].[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[c:6](-[c:15]2[c:16]([F:23])[cH:17][cH:18][c:19]([O:21][CH3:22])[cH:20]2)[cH:7][cH:8][c:9]([C:11](=[O:12])[O:13][CH3:14])[cH:10]1.[Cl:28][CH2:29][Cl:30]>>[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[c:6](-[c:15]2[c:16]([F:23])[cH:17][cH:18][c:19]([OH:21])[cH:20]2)[cH:7][cH:8][c:9]([C:11](=[O:12])[O:13][CH3:14])[cH:10]1

参加物

反応物 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 57705886Methyl 2-(1,1-dimethylethyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate

生成物 1

HCID 57706306Methyl 2-(1,1-dimethylethyl)-2'-fluoro-5'-hydroxy-1,1'-biphenyl-4-carboxylate

出典と根拠

ORDレコード: ord-17cf24feb6bd4a6d8fbc36c25fee6857
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…