5-(trifluoromethyl)pyridine-2-carboxylic Acid → N-(4'-Amino-5'-methylspiro[chroman-4,2'-imidazole]-6-yl)-5-(trifluoromethyl)picolinamide

HRID 155497

反応式

[CH3:14][C:15]1=[N:29][C:18]2([N:17]=[C:16]1[NH2:30])[CH2:19][CH2:20][O:21][c:22]1[cH:23][cH:24][c:25]([NH2:28])[cH:26][c:27]12.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9](=[O:10])[OH:11])[n:7][cH:8]1)([F:12])[F:13]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9](=[O:11])[NH:28][c:25]2[cH:24][cH:23][c:22]3[c:27]([cH:26]2)[C:18]2([N:17]=[C:16]([NH2:30])[C:15]([CH3:14])=[N:29]2)[CH2:19][CH2:20][O:21]3)[n:7][cH:8]1)([F:12])[F:13]