Dichloromethane → N-(4-fluorophenyl)-1-(6-(trifluoromethyl)-pyridin-3-yl)-3,4-dihydroisoquinoline-2(1H)-carboxamide

反応式

[Cl:31][CH2:32][Cl:33].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]2[NH:10][CH2:11][CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]32)[cH:7][n:8]1)([F:19])[F:20].[F:21][c:22]1[cH:23][cH:24][c:25]([N:28]=[C:29]=[O:30])[cH:26][cH:27]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]2[N:10]([C:29]([NH:28][c:25]3[cH:24][cH:23][c:22]([F:21])[cH:27][cH:26]3)=[O:30])[CH2:11][CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]32)[cH:7][n:8]1)([F:19])[F:20]

参加物

反応物 3

HCID 6344Dichloromethane

HCID 709554-Fluorophenyl isocyanate

HCID 595362781-(6-(Trifluoromethyl)pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline

生成物 1

HCID 59536388N-(4-fluorophenyl)-1-(6-(trifluoromethyl)-pyridin-3-yl)-3,4-dihydroisoquinoline-2(1H)-carboxamide

出典と根拠

ORDレコード: ord-1c365666398e43558c35cba0e90ced6c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…