Sodium ion → 2-{4-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1H-pyrazol-1-yl}ethanol

HRID 1564296ノート

反応式

HRID 1564296 の反応式
[Br:31][CH2:32][CH2:33][OH:34].[CH3:1][c:2]1[cH:3][c:4]([NH:18][c:19]2[n:20][cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]2)[cH:5][c:6](-[c:8]2[cH:9][n:10][c:11](-[c:13]3[cH:14][n:15][nH:16][cH:17]3)[s:12]2)[cH:7]1.[H-:30].[Na+:29].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[CH3:1][c:2]1[cH:3][c:4]([NH:18][c:19]2[n:20][cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]2)[cH:5][c:6](-[c:8]2[cH:9][n:10][c:11](-[c:13]3[cH:14][n:15]([CH2:32][CH2:33][OH:34])[n:16][cH:17]3)[s:12]2)[cH:7]1

参加物

6

反応物 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 108982-BromoethanolHCID 166653HydrideHCID 58456134N-{3-methyl-5-[2-(1H-pyrazol-4-yl)-1,3-thiazol-5-yl]phenyl}-4-(trifluoromethyl)pyrimidin-2-amine

生成物 1

HCID 584563002-{4-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1H-pyrazol-1-yl}ethanol

出典と根拠

ORDレコード
ord-a91b0f5c016c4cd5a5c513d57334f60b
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反応ノート

読み込み中…