1-(4-Chloro-3-methoxyphenyl)-3-methylpiperazine → 1-[4-(4-chloro-3-methoxyphenyl)-2-methylpiperazin-1-yl]-2-[3-(1H-imidazol-2-yl)pyrazolo[5,4-b]pyridin-1-yl]ethanone

反応式

[Cl:1][c:2]1[c:3]([O:15][CH3:16])[cH:4][c:5]([N:8]2[CH2:9][CH:10]([CH3:14])[NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[nH:17]1[c:18](-[c:22]2[n:23][n:24]([CH2:31][C:32](=[O:33])[OH:34])[c:25]3[n:26][cH:27][cH:28][cH:29][c:30]23)[n:19][cH:20][cH:21]1>>[Cl:1][c:2]1[c:3]([O:15][CH3:16])[cH:4][c:5]([N:8]2[CH2:9][CH:10]([CH3:14])[N:11]([C:32]([CH2:31][n:24]3[n:23][c:22](-[c:18]4[nH:17][cH:21][cH:20][n:19]4)[c:30]4[c:25]3[n:26][cH:27][cH:28][cH:29]4)=[O:33])[CH2:12][CH2:13]2)[cH:6][cH:7]1

参加物

反応物 2

HCID 671035981-(4-Chloro-3-methoxyphenyl)-3-methylpiperazine

HCID 1361746462-(3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

生成物 1

HCID 1358822371-[4-(4-chloro-3-methoxyphenyl)-2-methylpiperazin-1-yl]-2-[3-(1H-imidazol-2-yl)pyrazolo[5,4-b]pyridin-1-yl]ethanone

出典と根拠

ORDレコード: ord-038e387986264f1f9f0e2b01cb71e032
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…