Sulfur Dioxide → 2-(4-(4-((6-Chloro-5-fluoro-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)phenyl)-1,1,1,3,3,3-hexafluoro-2-propanol

HRID 157483

反応式

[Br:1][c:2]1[cH:3][c:4]([F:9])[c:5]([Cl:8])[n:6][cH:7]1.[CH2:61]([O:62][CH2:63][CH3:64])[CH3:65].[CH3:10][CH2:11][CH2:12][CH2:13][Li:14].[CH3:51][CH2:52][N:53]([CH2:54][CH3:55])[CH2:56][CH3:57].[Cl:18][N:19]1[C:20](=[O:21])[CH2:22][CH2:23][C:24]1=[O:25].[Cl:58][CH2:59][Cl:60].[F:26][C:27]([C:28]([C:29]([F:30])([F:31])[F:32])([OH:33])[c:34]1[cH:35][cH:36][c:37]([N:40]2[CH:41]([C:46]#[C:47][CH3:48])[CH2:42][NH:43][CH2:44][CH2:45]2)[cH:38][cH:39]1)([F:49])[F:50].[O:15]=[S:16]=[O:17]>>[c:2]1([S:16](=[O:15])(=[O:17])[N:43]2[CH2:42][CH:41]([C:46]#[C:47][CH3:48])[N:40]([c:37]3[cH:36][cH:35][c:34]([C:28]([C:27]([F:26])([F:49])[F:50])([C:29]([F:30])([F:31])[F:32])[OH:33])[cH:39][cH:38]3)[CH2:45][CH2:44]2)[cH:3][c:4]([F:9])[c:5]([Cl:8])[n:6][cH:7]1