Methanol → Methyl 7-methyl-9H-xanthene-2-carboxylate

HRID 1576135ノート

反応式

HRID 1576135 の反応式
[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([OH:18])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1.[CH3:19]O.S(=O)(=O)(O)O>O>[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([O:18][CH3:19])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 215006717-Methyl-9H-xanthene-2-carboxylic acid

生成物 1

HCID 21500836Methyl 7-methyl-9H-xanthene-2-carboxylate

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Twenty-six grams of 7-methylxanthene-2-carboxylic acid is added to 400 ml. of absolute methanol. To the resultant solution are added 18 ml. of concentrated sulfuric acid and the mixture is then heated at reflux for about two hours. The mixture is then cooled to 40° and sufficient water is added to bring the total volume to 1400 ml. The resultant mixture is then filtered to give methyl 7-methylxanthene-2-carboxylate.

後処理

  1. temperatureat reflux for about two hours
  2. temperatureThe mixture is then cooled to 40°
  3. filtrationThe resultant mixture is then filtered

出典と根拠

ORDレコード
ord-e517ac80cacc4e97bfa952cb8d6313b0
出典データセット
uspto-grants-1976_09
特許番号
US03979414

反応ノート

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