1-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetralone → 6,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

HRID 1576153ノート

反応式

HRID 1576153 の反応式
COC1C=CC2CC3C(=O)C(C)(C=2C=1)CCCC3.Cl[CH2:20][CH2:21][CH2:22][CH2:23][C:24]1([CH3:37])[C:33]2[C:28](=[CH:29][C:30]([O:34][CH3:35])=[CH:31][CH:32]=2)[CH2:27][CH2:26][C:25]1=[O:36]>>[CH3:35][O:34][C:30]1[CH:31]=[CH:32][C:33]2[C:24]3([CH3:37])[C:25](=[O:36])[CH:26]([CH2:20][CH2:21][CH2:22][CH2:23]3)[CH2:27][C:28]=2[CH:29]=1

参加物

3

反応物 2

HCID 214100831-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetraloneHCID 214101236,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen 12-one

生成物 1

HCID 214101276,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

実験手順

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen 12-one, there is obtained from 30.5 g. of 1-(4-chlorobutyl)-1-methyl-6-methoxy-2-tetralone 15 g. of the title product, b.p. 140° to 145° C. (0.5 mm.).

後処理

  1. customthere is obtained from 30.5 g

出典と根拠

ORDレコード
ord-b4104c4f96e2426f9bcf34962d963559
出典データセット
uspto-grants-1976_09
特許番号
US03979434

反応ノート

読み込み中…