Acetone → 2,2,5,5-Tetramethyl-1,3-thiazolidine-4-carboxylic acid
反応式
Cl.[NH2:2][CH:3]([C:8]([OH:10])=[O:9])[C:4]([SH:7])([CH3:6])[CH3:5].[CH3:11][C:12]([CH3:14])=O>>[CH3:5][C:4]1([CH3:6])[S:7][C:12]([CH3:14])([CH3:11])[NH:2][CH:3]1[C:8]([OH:10])=[O:9]参加物
3
実験手順
Ninety-three grams (0.5 mole) of D,L-penicillamine hydrochloride in 500 ml of acetone were heated at reflux temperature for 30 minutes under a nitrogen atmosphere. After distilling off the excess acetone there were obtained 113 grams of D,L-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid. The yield amounts to 99%.
後処理
- temperatureat reflux temperature for 30 minutes under a nitrogen atmosphere
- distillationAfter distilling off the excess acetone there
出典と根拠
- ORDレコード
- ord-d3810b3d329845aaab5dab9d9c145918
- 出典データセット
- uspto-grants-1976_09
- 特許番号
- US03980666
反応ノート
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