Potassium Hydroxide → 3-(4'-Fluoro-4-biphenylyl)-3-methyl-pyrazolidin-5-one
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3([CH3:20])[CH2:18][C:17](=N)[NH:16][NH:15]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[OH-:21].[K+]>C(O)(C)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3([CH3:20])[CH2:18][C:17](=[O:21])[NH:16][NH:15]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1参加物
4
実験手順
26.9 g of 3-(4'-fluoro-4-biphenylyl)-3-methyl-5-imino-pyrazolidine are boiled for 10 minutes with 150 ml of 2 N aqueous potassium hydroxide solution and 150 ml of isopropanol and the mixture is worked up in the usual manner to give 3-(4'-fluoro-4-biphenylyl)-3-methyl-pyrazolidin-5-one, m.p. 194°-196°.
出典と根拠
- ORDレコード
- ord-dd4f61f3730042448d52a7f3cc046c07
- 出典データセット
- uspto-grants-1976_09
- 特許番号
- US03980795
反応ノート
読み込み中…