Hydrochloric Acid → HCID 54500173、化合物

HRID 1576588ノート

反応式

HRID 1576588 の反応式
[CH3:1][C:2]([CH:7]=[CH:8][CH2:9][CH:10]([CH3:19])[CH2:11][CH2:12][CH2:13][C:14]([CH3:18])([CH3:17])[CH2:15][CH3:16])=[CH:3][C:4]([OH:6])=O.[CH3:20][CH2:21]OCC.C([Li])C.Cl>C1C=CC=CC=1>[CH3:1][C:2]([CH:7]=[CH:8][CH2:9][CH:10]([CH3:19])[CH2:11][CH2:12][CH2:13][C:14]([CH3:18])([CH3:17])[CH2:15][CH3:16])=[CH:3][C:4](=[O:6])[CH2:20][CH3:21]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 54353726HCID 54353726、化合物HCID 178506846HCID 178506846、化合物

生成物 1

HCID 54500173HCID 54500173、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

To a stirred solution of 2.5 g. of 3,7,11,11-tetramethyltrideca-2,4-dienoic acid in 30 ml. of dry ether is added slowly, at 0°, 23 ml. of a one molar solution of ethyl lithium in benzene. After about three hours at 20°, the mixture is poured into iced 1N hydrochloric acid (100 ml.) with vigorous stirring. The ether layer is separated, combined with ethereal washings of the aqueous phase, washed with water, saturated potassium bicarbonate, and then saturated brine, dried over magnesium sulfate and concentrated under reduced pressure to yield 5,9,13,13-tetramethylpentadeca-4,6-dien-3-one which is purified by high vacuum distillation or chromatography.

後処理

  1. customThe ether layer is separated
  2. washwashed with water, saturated potassium bicarbonate
  3. dry with materialsaturated brine, dried over magnesium sulfate
  4. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-fc87498485f34528a6a22bba822f5af6
出典データセット
uspto-grants-1976_09
特許番号
US03981922

反応ノート

読み込み中…