Methylamine → N-Methyl-N'-(trifluoromethyl)urea

Methylamine (3.1 grams; 0.1 mol) is placed into a glass ampule of 30 ml capacity and is cooled in an acetone-dry ice bath. Trifluoromethyl isocyanate (11.1 grams; 0.1 mol) is added to the ampule and the ampule is sealed. The reaction mixture is slowly warmed up to room temperature and is allowed to stand at this temperature for a period of about 1 hour. At the end of this time the ampule is opened and the contents removed and distilled under reduced pressure to yield N-methyl-N'-trifluoromethyl urea.

1. temperatureis cooled in an acetone-dry ice bath
2. customthe ampule is sealed
3. customthe contents removed
4. distillationdistilled under reduced pressure

ORDレコード

ord-fb71a6595c364851b5d0ba7a172432a5

出典データセット

uspto-grants-1976_09

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US03982019